A microglia’s fate in Alzheimer’s disease

The accumulation of neurotoxic amyloid beta peptides along with neurofibrillary tangle formation are key pathological hallmarks of Alzheimer’s disease. The brain has been considered as an immune-privileged organ…
Target engagement and dose response in clinical psychopharmacology

The dose-response relationship, driven by a drug’s engagement with its biological targets, is a foundational principle of clinical psychopharmacology…