Giovedì 14 marzo | Ore 14:30
Villa San Saverio, Via Valdisavoia 9 (CT)
INTERVIENE
Jay Sibbitts – University of Kansas
Dr. Sibbitts is a postdoctoral research fellow at working with Dr. Susan M. Lunte at the University of Kansas and is currently researching and developing methods to measure reactive nitrogen and oxygen species in brain cells using microfluidic devices and microchip electrophoresis. Dr. Sibbitts received his Bachelor of Science in Chemistry at Truman State University in 2014. He then went on to attend Kansas State University in the doctoral program in analytical chemistry where he worked with Dr. Christopher T. Culbertson. During his doctoral studies he worked on developing microfluidic devices to perform single-cell analysis to study cellular heterogeneity in T-lymphocytes and microglia. After completing his PhD in 2021, Dr. Sibbitts was selected to be a postdoctoral research fellow through the Institutional Research and Academic Career Development Award (IRACDA) program receiving a dual appointmentworking as a researcher at the University of Kansas and serving as an instructor in biochemistry at a local native American college, Haskell Indian Nations University. While working at the University of Kansas, Dr. Sibbitts has also engaged in an international collaboration with Dr. Giuseppe Caruso working on developing novel in vitro model systems to study Alzheimer’s disease and neuroinflammation.
ABSTRACT
The first publication featuring a microfluidic device, or “laboratory-on-a-chip”, was published in 1979 and reported a miniaturized gas chromatograph fabricated on a silicon wafer. In essence, “microfluidics” refers to small analytical devices with fluid-filled channels with dimensions in the range of 10s of micrometers that handle volumes down to the nanoliter and picoliter range.Since its inception, the field of microfluidics has grown significantly and now covers a remarkably wide variety of applications, particularly in the life sciences. Microfluidic devices have been used for disease diagnostics, wearable devices for biomarker measurements, miniature organ-on-a-chip model systems, single-cell analysis, among many other applications.A brief overview of microfluidic devices followed by a series of microfluidic applications at the cutting edge of research in the life sciences will be discussed.